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26 Feb Animal mitochondrial DNA recombination

Posted at 20:44h in Publications by davelunt

Lunt, D. H., and B. C. Hyman (1997) Nature 387:247-247.Â Animal mitochondrial DNA recombination

Genetic recombination is known to be a source of mitochondrial DNA (mtDNA) variability in plants, fungi and protists, but there continues to be a consensus (based on studies of somatic cell hybridization and DNA repair) that such processes do not operate on animal mtDNA. Contrary to this opinion we have now identified and characterized the end-products of recombination in the mitochondrial genome of the phytonematode Meloidogyne javanica.Â PDF PMID:Â 9153388

26 Feb Genomics and asexual reproduction in nematodes

Posted at 20:30h in Featured, Research by davelunt

Root Knot Nematodes of the genusÂ Meloidogyne are some of the world's most important crop pathogens. The genus contains a wide range of reproductive modes, with repeated transitions between them. This raises interesting possibilities to investigate the genomic consequences of the loss of meiotic recombination. I...

26 Feb Gene copy number variation in adaptive radiations

Posted at 20:23h in Featured, Research by davelunt

We are studying gene copy number variation (CNV) in adaptive radiations of cichlids. A fundamental question in biology is what type of genomic changes underlie local adaptation and species radiations. Cichlid fish radiations in the African Great Lakes show extraordinary levels of speciation and ecological...

21 Feb The Evolutionary Genomics of Sexual Reproduction

Posted at 22:20h in Slider by davelunt

How do recombination and reproductive mode determine genome content and architecture? We are carrying a large NERC-funded comparative genomics project to sequence nematode genomes with multiple independent losses of meiosis. ...

21 Feb The insect cytochrome oxidase I gene: evolutionary patterns and conserved primers for phylogenetic studies

Posted at 20:06h in Publications by davelunt

Lunt DH, Zhang DX, Szymura JM, Hewitt GM (1996)Â The insect cytochrome oxidase I gene: evolutionary patterns and conserved primers for phylogenetic studies.Â Insect Molecular Biology 5:153-65. PDF Insect mitochondrial cytochrome oxidase I (COI) genes are used as a model to examine the within-gene heterogeneity of evolutionary rate...

21 Feb The sequence and structure of the meadow grasshopper (Chorthippus parallelus) mitochondrial srRNA, ND2, COI, COII ATPase8 and 9 tRNA genes

Posted at 19:59h in Publications by davelunt

Szymura JM, Lunt DH, Hewitt GM (1996)Â The sequence and structure of the meadow grasshopper (Chorthippus parallelus) mitochondrial srRNA, ND2, COI, COII ATPase8 and 9 tRNA genes.Â Insect Molecular Biology 5:127-39. PDF The nucleotide sequence of the mitochondrial ND2, COI, COII, ATPase8, srRNA and nine tRNA genes have...