We are investigating how evolutionary forces shape the genome content and diversity using nematode model systems
We are involved with a range of projects in agri-tech applying modern genomic approaches to agriculture and forestry
Bioinformatics science that is open and reproducible. We develop software and protocols
We are investigating how genome structure and contentÂ change with the loss of meiotic recombination. This involves the sequencing and analysis of many nematode genomes in a phylogenetic design.
Modern high-throughput DNA sequencing techniques allowÂ a novelÂ understanding of ecological interactions. We are using metabarcoding techniques to study aphids and their parasitoids in agricultural ecosystems, and invasive oak processionary moths and oak tree insect communities.
Phylogenetics is an approach applied very broadly in biological sciences. Most approaches are manual however limiting the scale of the analysis. In addition it is almost impossible to reproduce this work. We are developing approaches to reproducible phylogenomics allowing rapid analysis of enormous datasets.
I teach courses to students and staff on basic bioinformatics skills. These have ranged fromÂ “Introduction to the command line” for those without much science computing background to “Reproducible metabarcoding” for those wishing to begin data analysis.
Root Knot Nematodes (Meloidogyne spp) causes large crop losses world wide. We are working to understand their origins, relationships, diversity, and pathogenic potential. Genome analysis has already demonstrated the importance of interspecific hybridization in creating the most devastating of the crop parasites.
We are developing both wet lab and bioinformatics approaches to environmental metabarcoding to greatly scale and refine the data.